Prof. Dr. Michael Hofreiter
Michael Hofreiter’ research activities focus on the effect environmental changes have on genetic diversity,adaptations and population dynamics in animals. He is especially interested in the use of ancient DNA sequences to directly observe changes in the genetic make-up of populations. Using this approach complete population replacements and migrations can be detected that could not be deciphered using traditional methodologies.
His team has developed a variety of technologies that allow using next generation DNA sequencing (NGS) for projects involving many individuals, which adapts NGS for research in evolutionary biology and population biology. Currently they are focusing on the use of DNA hybridisation capture technologies for obtaining complete mitochondrial genomes and large targeted nuclear DNA data sets for phylogenetic, population genetics and functional genetics studies using fossil DNA.